Will installing two M.2's reduce the peformance of a 5080? as I understand it may not be best to populate slot 2 but will it really be noticeable? it will purely be for gaming.
M.2_2 shares bandwidth with PCIEx16(G5) (i.e. GPU slot). Wen M.2_2 is occupied PCIEx16(G5) will ran at x8 speed [this is the GPU PCIe slot]
M.2_3 shares bandwidth with PCIEx16(G4). Wen M.2_3 is occupied PCIEx16(G4) will be disabled [this is the lower PCIe slot]
So you can either install your new SSD in the PCIe 4.0 M.2_3 slot and have the full bandwidth available to your GPU...or install it in the PCIe 5.0 M.2_2 slot and trust that there's plenty of bandwidth from the PCIe 5.0 slot for the 5080.